Tuesday, April 17, 2018

Scientists Have Accidentally Created a Mutant Enzyme That Eats Plastic Waste

They found the first ones in Japan. Hidden in the soil at a plastics recycling plant, researchers unearthed a microbe that had evolved to eat the soda bottles dominating its habitat, after you and I throw them away.

That discovery was announced in 2016, and scientists have now gone one better. While examining how the Japanese bug breaks down plastic, they accidentally created a mutant enzyme that outperforms the natural bacteria, and further tweaks could offer a vital solution to humanity's colossal plastics problem.

"Serendipity often plays a significant role in fundamental scientific research and our discovery here is no exception," says structural biologist John McGeehan from the University of Portsmouth in the UK.

"This unanticipated discovery suggests that there is room to further improve these enzymes, moving us closer to a recycling solution for the ever-growing mountain of discarded plastics."

834 mutant enzyme plastic pet 3John McGeehan (Stefan Venter/UPIX Photography)

McGeehan's team, including researchers at the US Department of Energy's National Renewable Energy Laboratory (NREL), stumbled onto their mutant tweak while investigating the crystal structure of PETase – the enzyme that helps the Japanese microbe, Ideonella sakaiensis, break down PET plastics (aka polyethylene terephthalate).

PET was patented back in the 1940s, and while that seems like a long time ago, in evolutionary terms it's pretty recent. The point being, while I. sakaiensis can indeed eat plastic, it's only lately had the opportunity to learn this trick, which means it doesn't munch real quick.

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